Acne: Causes, Types and Treatment

Acne: Causes, Types and Treatment — a common inflammatory condition of the pilosebaceous unit (the pore and its oil gland). It develops when excess sebum, dead skin cells and the bacterium C. acnes clog pores, leading to blackheads, whiteheads, papules, pustules, nodules or cysts.

Key points

  • Four drivers combine: excess oil, sticky dead-cell buildup, C. acnes bacteria and inflammation.
  • Non-inflammatory acne (blackheads, whiteheads) differs from inflammatory acne (red papules, pustules, painful nodules/cysts).
  • Evidence-based ingredients include salicylic acid, benzoyl peroxide, azelaic acid, retinoids and niacinamide.
  • Hormones, some cosmetics, friction and certain medications can trigger or worsen breakouts; picking increases scarring risk.

In this guide

Frequently asked

What actually causes acne?

A combination of excess sebum, clogged pores from dead skin cells, C. acnes bacteria and inflammation — not simply "dirty" skin or a single food.

Which ingredients treat acne best?

Salicylic acid, benzoyl peroxide, azelaic acid and topical retinoids are the most evidence-backed; persistent or cystic acne warrants a dermatologist's advice.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

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