Polyglutamic Acid

Polyglutamic Acid — a large water-loving polymer, produced by fermentation, that forms a thin film on the skin's surface and holds many times its weight in moisture. It works as a humectant, drawing water toward the outer layers of skin to leave it looking plump and smooth.

Key points

  • It is a high-molecular-weight humectant often described as holding significantly more water than hyaluronic acid, though results vary by formulation.
  • Because the molecule is large, it tends to sit on the skin surface and form a hydrating, breathable film rather than penetrating deeply.
  • It pairs well with hyaluronic acid, as the two can hydrate at different levels of the skin.
  • It is generally well tolerated across skin types and is a common choice in serums, essences, and lightweight moisturizers.

Frequently asked

Is polyglutamic acid better than hyaluronic acid?

Neither is strictly better; polyglutamic acid tends to form a surface film that limits water loss, while hyaluronic acid can hydrate at multiple depths, and many formulas combine both.

When should I apply a polyglutamic acid product?

It is typically applied to damp skin after cleansing and before richer creams, so the humectant can draw in and seal moisture.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

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