Tranexamic Acid

Tranexamic Acid — a synthetic derivative of the amino acid lysine used topically to help fade discoloration and even skin tone. It is thought to interrupt the interaction between skin cells and pigment-producing melanocytes, making it a popular choice for melasma and post-inflammatory hyperpigmentation.

Key points

  • Tranexamic acid was originally developed as an oral medication to reduce bleeding and is now widely used topically in skincare.
  • It helps limit excess pigment production by interfering with signaling between keratinocytes and melanocytes.
  • It is frequently studied and used for melasma, sun-induced spots, and post-inflammatory hyperpigmentation.
  • Topical tranexamic acid pairs well with ingredients like niacinamide, vitamin C, and sunscreen for tone-evening routines.

Frequently asked

What does tranexamic acid do for the skin?

Topically it helps reduce the appearance of dark spots and uneven tone by curbing the overproduction of melanin. It is especially associated with improving melasma and post-inflammatory hyperpigmentation.

Can tranexamic acid be combined with vitamin C?

Yes, tranexamic acid is commonly layered with vitamin C and niacinamide to support a brighter, more even complexion. Combining brightening actives with daily sunscreen helps maintain and protect results.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

Journal