Vitamin B5 (Panthenol)
Vitamin B5 (Panthenol) — the provitamin form of vitamin B5, known as panthenol, that converts to pantothenic acid in the skin and acts as a humectant to attract and hold moisture. It is widely used to soothe, hydrate, and support the skin barrier.
Key points
- Panthenol draws water into the skin, helping improve hydration and suppleness.
- It is studied for its soothing, calming qualities on irritated or compromised skin.
- It supports the skin barrier and can help reduce transepidermal water loss.
- Panthenol is gentle, widely tolerated, and common in products for sensitive skin.
Frequently asked
What is the difference between panthenol and pantothenic acid?
Panthenol is the provitamin that the skin converts into pantothenic acid, the active form of vitamin B5, which supports hydration and barrier function.
Is panthenol good for sensitive skin?
Yes, it is valued for its soothing and hydrating properties and is generally well tolerated, making it a frequent choice in formulas for sensitive skin.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

