Resveratrol

Resveratrol — a plant-derived polyphenol antioxidant found naturally in grape skins, red wine, and Japanese knotweed that is used topically to help neutralize free radicals and support a more even, resilient-looking complexion. In skincare it is valued for its antioxidant and skin-soothing properties, often paired with other actives to boost stability and performance.

Key points

  • Resveratrol is a stilbenoid antioxidant that helps defend skin against free radical damage caused by UV exposure and pollution.
  • It is naturally sourced from grapes, berries, peanuts, and Japanese knotweed, the last of which is a common commercial source.
  • Research suggests it may support a brighter, more even skin tone and help counter visible signs of environmental aging.
  • It is often formulated alongside vitamins like ferulic acid or applied at night, as it can degrade with light and air exposure.

Frequently asked

Can resveratrol be used with other antioxidants?

Yes, it is frequently combined with antioxidants such as vitamin E or ferulic acid, which can help stabilize the formula and enhance overall antioxidant protection.

Is resveratrol suitable for sensitive skin?

It is generally well tolerated and considered soothing, but as with any new active it is wise to patch test first and introduce it gradually.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

Encyclopedia

Further reading

This entry was written and checked against the sources below. They are published by clinical and scientific bodies, they are listed most readable first, and each one opens in a new tab. They are background for the whole entry rather than footnotes to individual sentences.

  1. Resveratrol as a factor preventing skin aging and affecting its regeneration PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov
  2. Resveratrol in Dermatological Therapy: A Critical Review PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov
  3. The impact of resveratrol on skin wound healing, scarring, and aging PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov
  4. Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately… PubMed Peer-reviewed (abstract) pubmed.ncbi.nlm.nih.gov
  5. Resveratrol as an active ingredient for cosmetic and dermatological applications: a review PubMed Peer-reviewed (abstract) pubmed.ncbi.nlm.nih.gov

SYNC does not publish medical advice. Nothing here replaces a consultation with a doctor or a pharmacist about your own skin.