Androgens and Sebum Production
Androgens and Sebum Production — a group of hormones, including testosterone and its potent derivative DHT, that stimulate the sebaceous glands to produce sebum. Their activity largely determines how oily the skin is and plays a central role in the development of acne.
Key points
- Androgens bind to receptors in sebaceous glands, prompting them to enlarge and secrete more sebum.
- The enzyme 5-alpha-reductase converts testosterone into DHT, a more potent driver of oil production within the skin.
- Rising androgen activity during puberty is a key reason acne commonly begins in the teenage years.
- Hormonal fluctuations, such as those around the menstrual cycle, can shift sebum output and trigger breakouts.
Frequently asked
Why does my skin get oilier at certain times of the month?
Cyclical shifts in hormones, including androgens, can increase sebaceous gland activity, leading to more oil and occasional breakouts around specific phases of the menstrual cycle.
Are androgens only relevant to acne in teenagers?
No; androgen-driven sebum production can influence oiliness and breakouts at any age, and adult hormonal acne is common, particularly along the lower face and jawline.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.
