Hyaluronic Acid
Hyaluronic Acid — a naturally occurring molecule in skin that can bind and hold large amounts of water, helping keep tissue hydrated and plump. In skincare it is a widely used humectant that draws moisture into the upper skin layers to improve the look of hydration and smoothness.
Key points
- Hyaluronic acid is a glycosaminoglycan naturally found in the skin and connective tissues.
- It is a humectant capable of binding many times its weight in water.
- Different molecular weights sit at different depths, with larger molecules staying near the surface and smaller ones penetrating further.
- In low-humidity conditions it can draw water from deeper skin, so it is often paired with an occlusive or moisturizer to seal in hydration.
Frequently asked
Does hyaluronic acid work for all skin types?
Hyaluronic acid is a lightweight humectant generally suitable for most skin types, including oily skin, though pairing it with a moisturizer helps lock in hydration.
Should hyaluronic acid be applied to damp or dry skin?
Applying it to slightly damp skin and following with a moisturizer helps it attract and retain water, especially in dry environments.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

