Fibroblast
Fibroblast — a key connective-tissue cell found in the dermis that produces collagen, elastin, and other components of the extracellular matrix. By generating these structural proteins, fibroblasts help maintain skin firmness, elasticity, and the framework that supports wound healing.
Key points
- Fibroblasts are the primary cells responsible for synthesizing collagen and elastin in the dermis.
- They also produce glycosaminoglycans, including hyaluronic acid, that help keep skin hydrated and plump.
- Fibroblasts play a central role in wound healing by building new connective tissue to repair damaged skin.
- Their activity tends to decline with age, contributing to reduced collagen production and loss of firmness over time.
Frequently asked
Why are fibroblasts important for skin aging?
Fibroblasts produce the collagen and elastin that keep skin firm and elastic, and their gradual slowdown with age is linked to thinner skin and reduced firmness.
What do fibroblasts do during wound healing?
During healing, fibroblasts multiply and produce new collagen and matrix material to rebuild the connective tissue that closes and strengthens a wound.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.
