Desquamation
Desquamation — the natural, controlled shedding of dead cells from the outermost layer of the skin. This process is regulated by enzymes that break the bonds holding surface cells together, allowing them to detach invisibly and keep the skin smooth.
Key points
- Desquamation is the final stage of the skin renewal process, releasing mature surface cells.
- Specialized enzymes dissolve the corneodesmosomes that bind cells together.
- Proper enzyme activity depends on adequate hydration and a slightly acidic pH.
- When desquamation is impaired, dead cells accumulate, causing flaking, roughness, or dullness.
- Exfoliating acids can support desquamation when the natural process is sluggish.
Frequently asked
What causes impaired desquamation?
Dryness, an altered skin pH, and reduced enzyme activity can slow desquamation, leading to visible flaking and a buildup of dead surface cells.
How does exfoliation relate to desquamation?
Chemical exfoliants like AHAs can assist the natural shedding process by loosening the bonds between surface cells when desquamation is sluggish.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.
