Skin Lipids
Skin Lipids — the fats that structure and protect the skin, including the ceramides, cholesterol, and free fatty acids that fill the spaces between surface cells. Together with sebum-derived lipids, they form the barrier that locks in moisture and keeps irritants out.
Key points
- Barrier lipids in the stratum corneum are dominated by ceramides, cholesterol, and free fatty acids.
- These lipids arrange into ordered layers that seal the spaces between skin cells.
- A balanced ratio of the three key lipids is important for effective barrier function.
- Lipid depletion increases water loss and leaves skin more prone to dryness and sensitivity.
- Skincare with ceramides and other lipids can help replenish and support the barrier.
Frequently asked
What is the difference between skin lipids and sebum?
Sebum is oil produced by sebaceous glands, while barrier lipids like ceramides are structural fats between skin cells; both contribute to a healthy protective surface.
Can lost skin lipids be replaced?
Skincare containing ceramides, cholesterol, and fatty acids can help replenish barrier lipids and support the skin's ability to retain moisture.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.
