Ingredients

PCA and Sodium PCA

PCA and Sodium PCA — closely related humectant ingredients, where PCA (pyrrolidone carboxylic acid) is a component of skin's natural moisturizing factor and sodium PCA is its salt form, both used to attract and hold water in the skin. They help keep the surface hydrated, supple, and comfortable.

Key points

  • Sodium PCA is a naturally occurring part of skin's own natural moisturizing factor, which helps maintain surface hydration.
  • As humectants, both draw water into the upper layers of skin to improve suppleness and reduce the look of dryness.
  • Sodium PCA is highly water-attracting and is prized as an effective, lightweight moisturizing ingredient.
  • They are generally gentle and suitable for most skin types, and pair well with occlusives that help seal in moisture.

Frequently asked

What is the difference between PCA and sodium PCA?

Sodium PCA is the sodium salt of PCA and is the more common, highly water-attracting form used in skincare, while both act as hydrating humectants.

Is sodium PCA good for dry skin?

Yes, as an effective humectant that mirrors part of skin's natural moisturizing factor, it helps hydrate and soften dry skin, especially alongside occlusive ingredients.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

Encyclopedia

Further reading

This entry was written and checked against the sources below. They are published by clinical and scientific bodies, they are listed most readable first, and each one opens in a new tab. They are background for the whole entry rather than footnotes to individual sentences.

  1. PCA - Cosmetics Info CosmeticsInfo Regulatory and safety cosmeticsinfo.org
  2. Safety Assessment of PCA (2-Pyrrolidone-5-Carboxylic Acid) and Its Salts as Used in Cosmetics Cosmetic Ingredient Review Regulatory and safety cir-safety.org
  3. Safety Assessment of PCA and Its Salts as Used in Cosmetics Cosmetic Ingredient Review Regulatory and safety cir-safety.org
  4. Direct or indirect skin lipid-ordering effect of pyrrolidone carboxylate sodium after topical treatment with penetration enhancers PubMed Peer-reviewed (abstract) pubmed.ncbi.nlm.nih.gov
  5. Moisturizers StatPearls (NCBI Bookshelf) Reference text ncbi.nlm.nih.gov
  6. Atopic Dermatitis and the Stratum Corneum: Part 1: The Role of Filaggrin in the Stratum Corneum Barrier and Atopic Skin PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov

SYNC does not publish medical advice. Nothing here replaces a consultation with a doctor or a pharmacist about your own skin.