Photolyase
Photolyase — a light-activated enzyme, sourced for cosmetics from organisms such as microalgae or bacteria, that helps repair a specific type of UV-induced DNA damage. In topical products it is intended to support the skin's natural recovery from sun exposure, and it relies on visible light to become active.
Key points
- Photolyase targets cyclobutane pyrimidine dimers, a common form of DNA damage caused by UV radiation.
- The enzyme is not naturally present in human skin and is typically derived from microorganisms like plankton or bacteria.
- It requires visible light to activate its repair function, a process known as photoreactivation.
- In cosmetics it is positioned as an after-sun or supportive ingredient rather than a substitute for sun protection.
Frequently asked
Does photolyase mean I can skip sunscreen?
No, photolyase is intended to support repair after exposure and does not prevent UV damage, so daily broad-spectrum sunscreen remains essential.
Why is photolyase often paired with light exposure?
Photolyase depends on visible light to activate its DNA-repair mechanism, a process called photoreactivation, which is why it works in daylight conditions.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.
