Oxidative Stress (Term)
Oxidative Stress (Term) — an imbalance between reactive molecules called free radicals and the body's ability to neutralize them with antioxidants, leading to potential damage to skin cells, proteins, and lipids. In the skin it is linked to visible signs of aging and is driven by factors such as ultraviolet light and pollution.
Key points
- Oxidative stress occurs when free radical production outpaces the skin's antioxidant defenses.
- External drivers include ultraviolet radiation, air pollution, and cigarette smoke, while normal metabolism also generates free radicals.
- Over time it can degrade collagen and elastin and contribute to fine lines, dullness, and uneven tone.
- Antioxidant ingredients such as vitamin C and vitamin E, paired with daily sun protection, are commonly used to help counter it.
Frequently asked
How does oxidative stress affect skin aging?
Free radical damage can break down collagen and elastin and impair skin cells, which contributes to wrinkles, loss of firmness, and uneven tone over time.
Do antioxidants stop oxidative stress?
Antioxidants help neutralize free radicals and reduce their impact, but they lessen rather than fully eliminate oxidative stress, so sun protection remains important.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

