Keratolytic
Keratolytic — an ingredient or agent that helps loosen and shed the outer layer of dead skin cells by weakening the bonds that hold corneocytes together. Common examples include salicylic acid and urea at higher concentrations, and such agents are often used to smooth rough skin and support unclogging of pores.
Key points
- Keratolytics promote desquamation by softening keratin and breaking down the cohesion between surface skin cells.
- Salicylic acid is a widely used keratolytic that is oil-soluble and can penetrate into sebum-filled pores.
- Other keratolytic agents include urea, lactic acid, and glycolic acid at appropriate concentrations.
- They are commonly used to address rough texture, buildup, and clogged pores.
- Overuse can cause dryness or irritation, so keratolytics are typically used at controlled concentrations.
Frequently asked
How is a keratolytic different from a moisturizer?
A keratolytic helps remove and loosen dead surface skin cells, whereas a moisturizer adds or retains hydration; some ingredients like urea can do both depending on concentration.
Is salicylic acid a keratolytic?
Yes, salicylic acid is a well-known keratolytic that helps shed dead skin cells and, because it is oil-soluble, can work within pores.
Related topics
This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.
