Cyst

Cyst — a large, soft, fluid- or pus-filled lesion that forms deep beneath the skin's surface, often appearing as a painful, swollen lump. Cystic lesions are among the most severe forms of acne and, like nodules, are strongly associated with scarring.

Key points

  • Cysts are typically softer than nodules because they contain fluid or pus rather than solid tissue.
  • They form deep within the skin and can be painful and slow to heal.
  • Cystic acne has a high likelihood of leaving scars or lasting marks.
  • These lesions generally do not respond well to over-the-counter treatments.
  • Attempting to pop or drain a cyst at home can worsen inflammation and scarring.

Frequently asked

What is the difference between a cyst and a nodule?

Both form deep in the skin, but a cyst is generally softer and filled with pus or fluid, while a nodule is firmer and more solid.

Why shouldn't I pop a cyst?

Cysts sit deep in the skin, and squeezing them can spread inflammation and raise the risk of scarring, so cystic acne is best managed by a dermatologist.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

Encyclopedia

Further reading

This entry was written and checked against the sources below. They are published by clinical and scientific bodies, they are listed most readable first, and each one opens in a new tab. They are background for the whole entry rather than footnotes to individual sentences.

  1. Nodulocystic acne DermNet NZ Clinical guidance dermnetnz.org
  2. Tips to treat a deep, painful pimple American Academy of Dermatology Clinical guidance aad.org
  3. What can clear severe acne? American Academy of Dermatology Clinical guidance aad.org
  4. Isotretinoin: The truth about safety, side effects, and skin care American Academy of Dermatology Clinical guidance aad.org
  5. Isotretinoin StatPearls (NCBI Bookshelf) Reference text ncbi.nlm.nih.gov
  6. Acne Conglobata StatPearls (NCBI Bookshelf) Reference text ncbi.nlm.nih.gov

SYNC does not publish medical advice. Nothing here replaces a consultation with a doctor or a pharmacist about your own skin.