Asiaticoside

Asiaticoside — a triterpenoid saponin derived from Centella Asiatica, recognized in research for its role in supporting skin repair and collagen synthesis. Alongside madecassoside, it is one of the glycoside actives that give centella its soothing reputation. It is typically used in formulas focused on barrier recovery and skin comfort.

Key points

  • It is the glycoside form of asiatic acid, one of centella's four core triterpenoids.
  • Laboratory studies associate asiaticoside with wound-healing support and stimulation of collagen production.
  • It is commonly paired with madecassoside in centella-based soothing products.
  • It contributes antioxidant activity that may help defend skin against environmental stress.

Frequently asked

What does asiaticoside do in skincare?

It is used to soothe skin and support the barrier, and research links it to collagen synthesis and skin-repair processes.

How is asiaticoside different from asiatic acid?

Asiaticoside is the sugar-bound (glycoside) form of asiatic acid, which can affect how the compound behaves and is absorbed in a formula.

Related topics

This is a foundational entry in the SYNC Skin Encyclopedia and is expanded over time. Educational information only — not medical advice.

Encyclopedia

Further reading

This entry was written and checked against the sources below. They are published by clinical and scientific bodies, they are listed most readable first, and each one opens in a new tab. They are background for the whole entry rather than footnotes to individual sentences.

  1. Centella asiatica - LiverTox StatPearls (NCBI Bookshelf) Reference text ncbi.nlm.nih.gov
  2. Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov
  3. Therapeutic properties and pharmacological activities of Centella asiatica PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov
  4. Burn wound healing properties of asiaticoside and madecassoside PubMed Peer-reviewed (abstract) pubmed.ncbi.nlm.nih.gov
  5. Biochemistry, Collagen Synthesis StatPearls (NCBI Bookshelf) Reference text ncbi.nlm.nih.gov
  6. Age-related dermal collagen changes during development, maturation and ageing – a morphometric and comparative study PubMed Central Peer-reviewed, open access pmc.ncbi.nlm.nih.gov

SYNC does not publish medical advice. Nothing here replaces a consultation with a doctor or a pharmacist about your own skin.